Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | METAP2 | P50579 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11133082 | 1.00 | MAPT (0.61) | MAPTNPC1RAB9AMETAP2APP | |
| SCHEMBL14874538 | 0.89 | METAP2 (0.53) | MAPTNPC1RAB9AMETAP2APP | |
| SCHEMBL14874539 | 0.89 | METAP2 (0.53) | MAPTNPC1RAB9AMETAP2APP | |
| SCHEMBL31385202 | 0.85 | METAP2 (0.50) | MAPTNPC1RAB9AMETAP2APP | |
| SCHEMBL8956458 | 0.85 | METAP2 (0.50) | MAPTNPC1RAB9AMETAP2APP | |
| SCHEMBL9170800 | 0.82 | APP (0.78) | MAPTNPC1RAB9AAPPFBP1 | |
| SCHEMBL458177 | 0.82 | APP (0.78) | MAPTNPC1RAB9AAPPFBP1 | |
| SCHEMBL14947048 | 0.82 | APP (0.78) | MAPTNPC1RAB9AAPPFBP1 | |
| SCHEMBL458178 | 0.82 | APP (0.78) | MAPTNPC1RAB9AAPPFBP1 | |
| SCHEMBL9170804 | 0.82 | APP (0.78) | MAPTNPC1RAB9AAPPFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4399206-A | Disazo electrophotographic photosensitive member | CANON KABUSHIKI KAISHA (JP) | 1983-08-16 | — | — | US | disclosed |