Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.45 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.44 |
| ▸ | CLIC1 | O00299 | 1/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11342054 | 0.81 | CXCL8 (0.44) | PTGS2CXCL8CLIC1CLCN2ABCB11 | |
| SCHEMBL11340774 | 0.80 | CLCN2 (0.69) | PTGS2CXCL8CLIC1CLCN2ABCB11 | |
| SCHEMBL8957020 | 0.79 | KMT2A (0.41) | PTGS2CXCL8CLIC1CLCN2ABCB11 | |
| SCHEMBL8956861 | 0.79 | PTGS2 (0.72) | PTGS2CXCL8CLIC1CLCN2ABCB11 | |
| SCHEMBL8956419 | 0.79 | PTGS2 (0.54) | PTGS2CXCL8CLIC1CLCN2ABCB11 | |
| Eltenac SCHEMBL145080 | 0.78 | PTGS2 (0.67) | PTGS2CXCL8CLIC1CLCN2ABCB11 | |
| SCHEMBL11346687 | 0.76 | PTGS2 (0.51) | PTGS2CXCL8CLIC1CLCN2ABCB11 | |
| SCHEMBL11346658 | 0.75 | PTGS2 (0.59) | PTGS2CXCL8CLIC1CLCN2ABCB11 | |
| SCHEMBL11353757 | 0.75 | PTGS2 (0.67) | PTGS2CXCL8CLIC1CLCN2ABCB11 | |
| SCHEMBL11351526 | 0.73 | PTGS2 (0.49) | PTGS2CXCL8CLIC1CLCN2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338494-B1 | 3-Anilino-2-hydroxycarbonyl-4-thiophen-acetic acids | BYK GULDEN LOMBERG CHEM FAB (DE) | 1996-01-10 | — | — | EP | disclosed |
| EP-0338494-A2 | 3-Anilino-2-hydroxycarbonyl-4-thiophen-acetic acids | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1989-10-25 | — | — | EP | disclosed |