SCHEMBL8956945

SCHEMBL8956945

C#CC(OC(=O)C(=C)C#N)[Si](C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL420702 0.80 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL604548 0.77 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL602481 0.76 ALDH1A1 (0.50) ALDH1A1TSHR
SCHEMBL230496 0.71 ALDH1A1 (0.52) ALDH1A1TSHR
SCHEMBL5889388 0.71 ALDH1A1 (0.57) ALDH1A1TSHR
SCHEMBL11809874 0.70 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL6288806 0.70 ALDH1A1 (0.50) ALDH1A1TSHR
SCHEMBL448845 0.69 TSHR (0.55) ALDH1A1TSHR
SCHEMBL11799300 0.69 TSHR (0.55) ALDH1A1TSHR
SCHEMBL10627188 0.68 ALDH1A1 (0.48) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0502128-B1 ANIONICALLY POLYMERIZABLE MONOMERS, POLYMERS THEREOF, AND USE OF SUCH POLYMERS IN PHOTORESISTS LOCTITE CORP (US) 1996-01-03 EP disclosed
EP-0502128-A1 ANIONICALLY POLYMERIZABLE MONOMERS, POLYMERS THEREOF, AND USE OF SUCH POLYMERS IN PHOTORESISTS. LOCTITE CORP (US) 1992-09-09 EP disclosed
EP-0502128-A4 ANIONICALLY POLYMERIZABLE MONOMERS, POLYMERS THEREOF, AND USE OF SUCH POLYMERS IN PHOTORESISTS. LOCTITE CORP (US) 1992-04-02 EP disclosed
WO-1991007446-A1 ANIONICALLY POLYMERIZABLE MONOMERS, POLYMERS THEREOF, AND USE OF SUCH POLYMERS IN PHOTORESISTS LOCTITE CORPORATION (US) 1991-05-30 WO disclosed