Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957165 | 0.95 | LTB4R (0.87) | LTB4RLTB4R2 | |
| SCHEMBL8941563 | 0.94 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL8957078 | 0.93 | LTB4R (0.76) | LTB4RLTB4R2 | |
| SCHEMBL9198703 | 0.92 | LTB4R (0.77) | LTB4RLTB4R2 | |
| SCHEMBL9201024 | 0.90 | LTB4R (0.71) | LTB4RLTB4R2 | |
| SCHEMBL8941432 | 0.88 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL8957196 | 0.88 | LTB4R (0.73) | LTB4RLTB4R2 | |
| SCHEMBL9196330 | 0.87 | LTB4R (0.80) | LTB4RLTB4R2 | |
| SCHEMBL8877600 | 0.87 | LTB4R (0.85) | LTB4RLTB4R2 | |
| SCHEMBL9372746 | 0.86 | LTB4R (0.67) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532383-A | Leukotriene B4 antagonists | G. D. SEARLE & CO. (US) | 1996-07-02 | — | — | US | disclosed |
| EP-0593478-B1 | LEUKOTRIENE B 4 ANTAGONISTS | SEARLE & CO (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5439937-A | Leukotriene B4 antagonists | G. D. SEARLE & CO. (US) | 1995-08-08 | — | — | US | disclosed |
| US-5310951-A | Benzopyran-2-propanoic acid derivatives; antiinflammatory agents | G.D. SEARLE & CO. (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0593478-A1 | LEUKOTRIENE B 4? ANTAGONISTS. | SEARLE & CO (US) | 1994-04-27 | — | — | EP | disclosed |
| US-5124350-A | Antiinflammatory agent | G. D. SEARLE & CO. (US) | 1992-06-23 | — | — | US | disclosed |
| WO-1992000011-A2 | LEUKOTRIENE B4 ANTAGONISTS | G.D. SEARLE & CO. (US) | 1992-01-09 | — | — | WO | disclosed |