Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093585 | 0.88 | APP (0.55) | APPGAAPTGS1PTGS2MAOA | |
| SCHEMBL492221 | 0.87 | APP (0.70) | APPPTGS1PTGS2MAOAMAOB | |
| SCHEMBL20328414 | 0.87 | APP (0.70) | APPPTGS1PTGS2MAOAMAOB | |
| SCHEMBL20328415 | 0.87 | APP (0.70) | APPPTGS1PTGS2MAOAMAOB | |
| Hydrochloric Acid SCHEMBL15269629 | 0.85 | APP (0.68) | APPPTGS1PTGS2MAOAMAOB | |
| Ethane SCHEMBL10589507 | 0.85 | APP (0.68) | APPPTGS1PTGS2MAOAMAOB | |
| SCHEMBL31096483 | 0.85 | APP (0.68) | APPPTGS1PTGS2MAOAMAOB | |
| SCHEMBL28853641 | 0.85 | APP (0.68) | APPPTGS1PTGS2MAOAMAOB | |
| SCHEMBL27548370 | 0.85 | APP (0.68) | APPPTGS1PTGS2MAOAMAOB | |
| SCHEMBL10924203 | 0.84 | PKM (0.70) | APPGAAPTGS1PTGS2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600339-B1 | Method for the preparation of sodium salts of aromatic sulphinic acids containing nitro groups | BAYER AG (DE) | 1996-01-10 | — | — | EP | disclosed |
| EP-0600339-A1 | Method for the preparation of sodium salts of aromatic sulphinic acids containing nitro groups | BAYER AG (DE) | 1994-06-08 | — | — | EP | disclosed |