Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697384 | 0.83 | P2RY10 (0.45) | PTPN1PTPRCITGB3ITGA2B | |
| SCHEMBL8935176 | 0.82 | P2RY10 (0.41) | PTPN1PTPRCITGB3ITGA2BSLC7A5 | |
| SCHEMBL8692789 | 0.82 | ITGB3 (0.47) | PTPN1ITGB3ITGA2B | |
| SCHEMBL8957176 | 0.78 | P2RY10 (0.41) | — | |
| SCHEMBL17997501 | 0.72 | PTPN1 (0.55) | PTPN1PTPRCITGB3ITGA2BSLC7A5 | |
| SCHEMBL7025170 | 0.72 | PTPRC (0.52) | PTPN1PTPRCITGB3ITGA2BSLC7A5 | |
| SCHEMBL29123731 | 0.72 | PTPRC (0.52) | PTPN1PTPRCITGB3ITGA2BSLC7A5 | |
| SCHEMBL524638 | 0.72 | ITGB3 (0.59) | PTPN1PTPRCITGB3ITGA2BSLC7A5 | |
| SCHEMBL455152 | 0.72 | ITGB3 (0.59) | PTPN1PTPRCITGB3ITGA2BSLC7A5 | |
| SCHEMBL9784912 | 0.72 | ITGB3 (0.59) | PTPN1PTPRCITGB3ITGA2BSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554728-A | Lipid conjugates of therapeutic peptides and protease inhibitors | NEXSTAR PHARMACEUTICALS, INC. (US) | 1996-09-10 | — | — | US | claimed |
| US-5554728-A | Lipid conjugates of therapeutic peptides and protease inhibitors | NEXSTAR PHARMACEUTICALS, INC. (US) | 1996-09-10 | — | — | US | disclosed |