Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | TPH1 | P17752 | 2/20 | 0.47 |
| ▸ | GRB2 | P62993 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455152 | 1.00 | ITGB3 (0.59) | ITGB3ITGA2BSLC7A5PTPN1PTGS1 | |
| SCHEMBL9784912 | 1.00 | ITGB3 (0.59) | ITGB3ITGA2BSLC7A5PTPN1PTGS1 | |
| Hydrochloric Acid SCHEMBL6775024 | 0.98 | ITGB3 (0.58) | ITGB3ITGA2BSLC7A5PTPN1PTGS1 | |
| SCHEMBL8195266 | 0.88 | CA12 (0.46) | ITGB3ITGA2BPTPN1CA12CA1 | |
| SCHEMBL25937506 | 0.88 | NPC1 (0.47) | ITGB3ITGA2BPTPN1CA12CA1 | |
| SCHEMBL19512314 | 0.88 | SLC1A1 (0.58) | ITGB3ITGA2BSLC7A5PTPN1CA12 | |
| SCHEMBL19512315 | 0.88 | SLC1A1 (0.58) | ITGB3ITGA2BSLC7A5PTPN1CA12 | |
| SCHEMBL19512313 | 0.88 | SLC1A1 (0.58) | ITGB3ITGA2BSLC7A5PTPN1CA12 | |
| SCHEMBL16060571 | 0.86 | ITGB3 (0.61) | ITGB3ITGA2BSLC7A5PTPN1PTGS1 | |
| SCHEMBL1944103 | 0.86 | LDHA (0.57) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 402 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250325632-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES | Synthorx, Inc. (US) | 2025-10-23 | — | — | US | claimed |
| US-20250325633-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES | Synthorx, Inc. (US) | 2025-10-23 | — | — | US | claimed |
| US-12377131-B2 | Cytokine conjugates for the treatment of autoimmune diseases | Synthorx, Inc. (US) | 2025-08-05 | — | — | US | claimed |
| US-12318431-B2 | Cytokine conjugates for the treatment of proliferative and infectious diseases | Synthorx, Inc. (US) | 2025-06-03 | — | — | US | claimed |
| US-20240082359-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES | Synthorx, Inc. (US) | 2024-03-14 | — | — | US | claimed |
| US-11919934-B2 | IL-15 conjugates and uses thereof | Synthorx, Inc. (US) | 2024-03-05 | — | — | US | claimed |
| US-20230302089-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES | Synthorx, Inc. (US) | 2023-09-28 | — | — | US | claimed |
| US-11701407-B2 | Cytokine conjugates for the treatment of proliferative and infectious diseases | Synthorx, Inc. (US) | 2023-07-18 | — | — | US | claimed |
| US-11622993-B2 | Cytokine conjugates for the treatment of autoimmune diseases | Synthorx, Inc. (US) | 2023-04-11 | — | — | US | claimed |
| EP-4041247-A1 | EUKARYOTIC SEMI-SYNTHETIC ORGANISMS | The Scripps Research Institute (US) | 2022-08-17 | — | — | EP | claimed |
| CN-111194322-A | Cytokine conjugates for the treatment of proliferative and infectious diseases | 辛索克斯公司 | 2020-05-22 | — | — | CN | claimed |
| CN-111183149-A | Cytokine conjugates for the treatment of autoimmune diseases | 辛索克斯公司 | 2020-05-19 | — | — | CN | claimed |
| WO-2019165453-A1 | IL-15 CONJUGATES AND USES THEREOF | Synthorx, Inc. (US) | 2019-08-29 | — | — | WO | claimed |
| WO-2019028425-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES | Synthorx, Inc. (US) | 2019-02-07 | — | — | WO | claimed |
| WO-2019028419-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES | Synthorx, Inc. (US) | 2019-02-07 | — | — | WO | claimed |
| EP-2665744-B1 | MACROCYCLIC COMPOUNDS WITH A HYBRID PEPTIDIC/NON-PEPTIDIC BACKBONE AND METHODS FOR THEIR PREPARATION | UNIV ROCHESTER (US) | 2015-04-08 | — | — | EP | claimed |
| US-8986953-B2 | Macrocyclic compounds with a hybrid peptidic/non-peptidic backbone and methods for their preparation | UNIVERSITY OF ROCHESTER (US) | 2015-03-24 | — | — | US | claimed |
| US-20130330773-A1 | MACROCYCLIC COMPOUNDS WITH A HYBRID PEPTIDIC/NON-PEPTIDIC BACKBONE AND METHODS FOR THEIR PREPARATION | NATIONAL SCIENCE FOUNDATION | 2013-12-12 | — | — | US | claimed |
| EP-2665744-A2 | MACROCYCLIC COMPOUNDS WITH A HYBRID PEPTIDIC/NON-PEPTIDIC BACKBONE AND METHODS FOR THEIR PREPARATION | UNIVERSITY OF ROCHESTER (US) | 2013-11-27 | — | — | EP | claimed |
| WO-2012100176-A2 | MACROCYCLIC COMPOUNDS WITH A HYBRID PEPTIDIC/NON-PEPTIDIC BACKBONE AND METHODS FOR THEIR PREPARATION | UNIVERSITY OF ROCHESTER (US) | 2012-07-26 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325633-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES | IL2, IL2RA, IL15 | ITGB3 1343/4885ITGA2B 284/4885SLC7A5 2484/4885 |
| US-20230302089-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES | IL2, IL2RA, IL15 | ITGB3 1343/4885ITGA2B 284/4885SLC7A5 2484/4885 |
| US-11701407-B2 | Cytokine conjugates for the treatment of proliferative and infectious diseases | IL2, IL2RA, IL36G | ITGB3 959/4885ITGA2B 286/4885SLC7A5 1836/4885 |
| US-12318431-B2 | Cytokine conjugates for the treatment of proliferative and infectious diseases | IL2, IL2RA, IL36G | ITGB3 959/4885ITGA2B 286/4885SLC7A5 1836/4885 |
| US-20240082359-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES | IL2, IL2RA, IL36G | ITGB3 959/4885ITGA2B 286/4885SLC7A5 1836/4885 |
| US-20130330773-A1 | MACROCYCLIC COMPOUNDS WITH A HYBRID PEPTIDIC/NON-PEPTIDIC BACKBONE AND METHODS FOR THEIR PREPARATION | MICA, VIP, NPEPPS | ITGB3 4870/4885ITGA2B 4855/4885SLC7A5 964/4885 |
| US-20250325632-A1 | CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES | IL2, IL2RA, IL36G | ITGB3 959/4885ITGA2B 286/4885SLC7A5 1836/4885 |
| US-12377131-B2 | Cytokine conjugates for the treatment of autoimmune diseases | IL2, IL2RA, IL15 | ITGB3 1343/4885ITGA2B 284/4885SLC7A5 2484/4885 |
| US-11622993-B2 | Cytokine conjugates for the treatment of autoimmune diseases | IL2, IL2RA, IL15 | ITGB3 1343/4885ITGA2B 284/4885SLC7A5 2484/4885 |
| US-11919934-B2 | IL-15 conjugates and uses thereof | IL15, IL15RA, IL2 | ITGB3 225/4885ITGA2B 250/4885SLC7A5 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.