SCHEMBL8957256

SCHEMBL8957256

CCc1ccc([N+](=O)[O-])cc1.O=S(=O)(O)Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
TSHR P16473 1/20 0.50
ALDH1A1 P00352 4/20 0.49
LOXL2 Q9Y4K0 1/20 0.48
CYP2C19 P33261 2/20 0.47
CA2 P00918 5/20 0.46
CA1 P00915 4/20 0.46
CA12 O43570 3/20 0.46
CA9 Q16790 3/20 0.46
CA14 Q9ULX7 3/20 0.46
CA3 P07451 2/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA5A P35218 2/20 0.46
CA7 P43166 2/20 0.46
CA13 Q8N1Q1 2/20 0.46
CA5B Q9Y2D0 2/20 0.46
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL128402 0.87 LOXL2 (0.61) MAPTMEN1KMT2ATSHRALDH1A1
Ammonia Solution, Strong SCHEMBL4739223 0.85 LOXL2 (0.59) MAPTMEN1KMT2ATSHRALDH1A1
Bromide SCHEMBL2771283 0.85 LOXL2 (0.59) MAPTMEN1KMT2ATSHRALDH1A1
Bicarbonate SCHEMBL31202990 0.83 MAPT (0.55) MAPTMEN1KMT2ATSHRALDH1A1
SCHEMBL27616776 0.81 MEN1 (0.45) MAPTMEN1KMT2ATSHRALDH1A1
SCHEMBL14071658 0.81 LOXL2 (0.55) MAPTMEN1KMT2ATSHRALDH1A1
SCHEMBL10915611 0.81 POLB (0.63) MAPTMEN1KMT2ATSHRALDH1A1
Nitrobenzene SCHEMBL28048278 0.80 ALDH1A1 (0.50) MAPTMEN1KMT2ATSHRALDH1A1
4-Nitrotoluene SCHEMBL8957077 0.79 ACHE (0.72) MAPTMEN1KMT2AALDH1A1CA2
Butane SCHEMBL9095012 0.77 LOXL2 (0.52) MAPTMEN1KMT2ATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0600339-B1 Method for the preparation of sodium salts of aromatic sulphinic acids containing nitro groups BAYER AG (DE) 1996-01-10 EP disclosed
EP-0600339-A1 Method for the preparation of sodium salts of aromatic sulphinic acids containing nitro groups BAYER AG (DE) 1994-06-08 EP disclosed