Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15941603 | 0.94 | KMT2A (0.61) | KMT2ANR4A2KDM4EPLA2G4BNR1H4 | |
| SCHEMBL10787479 | 0.86 | KMT2A (0.80) | KMT2ANR4A2PLA2G4BNR1H4POLB | |
| SCHEMBL30167982 | 0.86 | KMT2A (0.80) | KMT2ANR4A2PLA2G4BNR1H4POLB | |
| SCHEMBL6932542 | 0.82 | KMT2A (0.75) | KMT2ANR4A2PLA2G4BNR1H4POLB | |
| SCHEMBL10999317 | 0.82 | KMT2A (0.47) | KMT2AKDM4EPOLB | |
| SCHEMBL9803295 | 0.82 | KMT2A (0.80) | KMT2ANR4A2PLA2G4BNR1H4POLB | |
| SCHEMBL8957481 | 0.81 | PKM (0.64) | NR4A2PLA2G4BPKM | |
| SCHEMBL19665046 | 0.81 | KMT2A (0.73) | KMT2ANR4A2PLA2G4BNR1H4POLB | |
| SCHEMBL4509654 | 0.81 | KMT2A (0.77) | KMT2ANR4A2PLA2G4BNR1H4AKR1C3 | |
| SCHEMBL11080434 | 0.80 | CHRNB2 (0.51) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689435-A1 | USE OF SUBSTITUTED ALKYL NITRATES FOR THE TREATMENT OF PATHOLOGICALLY INCREASED INTRA-OCULAR PRESSURE | BYK NEDERLAND BV (NL) | 1996-01-03 | — | — | EP | claimed |
| WO-1994021248-A1 | USE OF SUBSTITUTED ALKYL NITRATES FOR THE TREATMENT OF PATHOLOGICALLY INCREASED INTRA-OCULAR PRESSURE | BYK NEDERLAND BV (NL) | 1994-09-29 | — | — | WO | claimed |
| EP-0689435-A1 | USE OF SUBSTITUTED ALKYL NITRATES FOR THE TREATMENT OF PATHOLOGICALLY INCREASED INTRA-OCULAR PRESSURE | BYK NEDERLAND BV (NL) | 1996-01-03 | — | — | EP | disclosed |
| WO-1994021248-A1 | USE OF SUBSTITUTED ALKYL NITRATES FOR THE TREATMENT OF PATHOLOGICALLY INCREASED INTRA-OCULAR PRESSURE | BYK NEDERLAND BV (NL) | 1994-09-29 | — | — | WO | disclosed |