Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8627165 | 0.99 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL6930491 | 0.94 | SMN1; SMN2 (0.39) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL8625168 | 0.93 | MLYCD (0.40) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL6296583 | 0.90 | SMN1; SMN2 (0.40) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL5966898 | 0.87 | SMN1; SMN2 (0.40) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL5966823 | 0.86 | SMN1; SMN2 (0.42) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL8626795 | 0.80 | TSHR (0.44) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL9298715 | 0.79 | SMN1; SMN2 (0.45) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| Trifluoroacetic Acid SCHEMBL8626777 | 0.79 | MLYCD (0.48) | MLYCDF2 | |
| SCHEMBL1822076 | 0.78 | MLYCD (0.44) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689549-A1 | NEW UREA DERIVATES, THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-03 | — | — | EP | disclosed |
| WO-1994022907-A1 | NEW UREA DERIVATES, THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |