Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL834204 | 0.86 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2SPHK2NR4A1 | |
| SCHEMBL8957448 | 0.85 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27554309 | 0.85 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8572591 | 0.85 | SMN1; SMN2 (0.55) | NPC1RAB9ASMN1; SMN2SPHK2NR4A1 | |
| SCHEMBL1222408 | 0.84 | ITGB3 (0.73) | NPC1RAB9ASMN1; SMN2SPHK2NR4A1 | |
| SCHEMBL28891518 | 0.84 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| Monobenzone SCHEMBL8957440 | 0.83 | ITGB3 (0.64) | NPC1RAB9ASMN1; SMN2SPHK2NR4A1 | |
| SCHEMBL832428 | 0.83 | HDAC1 (0.56) | NPC1RAB9ASMN1; SMN2SPHK2NR4A1 | |
| SCHEMBL1222607 | 0.83 | RAB9A (0.65) | NPC1RAB9ASMN1; SMN2SPHK2NR4A1 | |
| SCHEMBL25870996 | 0.82 | NR4A1 (0.66) | NPC1RAB9ASMN1; SMN2SPHK2NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527523-A | PIGMENT-REMOVING ACTIVITY | VIRBAC S.A. (FR) | 1996-06-18 | — | — | US | disclosed |