Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27554309 | 0.90 | SMN1; SMN2 (0.56) | SMN1; SMN2GLAMMP1GAAPRSS1 | |
| SCHEMBL28891518 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2GLAMMP1GAAPRSS1 | |
| SCHEMBL8957429 | 0.85 | NPC1 (0.62) | SMN1; SMN2RAB9ANPC1HTTALDH1A1 | |
| Hippuric Acid SCHEMBL8957458 | 0.80 | HIF1A (0.59) | SMN1; SMN2GAARAB9ANPC1LMNA | |
| SCHEMBL5655365 | 0.78 | PRSS1 (0.68) | SMN1; SMN2GLAMMP1GAAPRSS1 | |
| SCHEMBL27998181 | 0.78 | LTA4H (0.54) | GLAGAAHPGDELANEHTT | |
| SCHEMBL10915714 | 0.78 | ATM (0.62) | SMN1; SMN2GAARAB9AHPGDNPC1 | |
| SCHEMBL5783639 | 0.77 | KMT2A (0.43) | SMN1; SMN2GLAGAAELANEHTT | |
| Monobenzone SCHEMBL8957440 | 0.77 | ITGB3 (0.64) | SMN1; SMN2RAB9ANPC1HTTALDH1A1 | |
| SCHEMBL3961994 | 0.76 | GAA (0.59) | SMN1; SMN2GLAGAAPRSS1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527523-A | PIGMENT-REMOVING ACTIVITY | VIRBAC S.A. (FR) | 1996-06-18 | — | — | US | disclosed |