Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | ITGAL | P20701 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888677 | 0.91 | — | — | |
| SCHEMBL6897079 | 0.83 | CCKBR (0.51) | — | |
| SCHEMBL6897076 | 0.83 | CCKBR (0.51) | — | |
| SCHEMBL8829919 | 0.78 | — | — | |
| SCHEMBL7047252 | 0.78 | CCKBR (0.44) | — | |
| SCHEMBL6896285 | 0.77 | ACE (0.41) | — | |
| SCHEMBL8829874 | 0.77 | ACE (0.41) | — | |
| SCHEMBL6896286 | 0.77 | ACE (0.41) | — | |
| SCHEMBL9085204 | 0.76 | TACR1 (0.44) | — | |
| SCHEMBL8893462 | 0.76 | ACE (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554643-A | Pro-drugs for CCK antagonists | WARNER-LAMBERT COMPANY (US) | 1996-09-10 | — | — | US | disclosed |
| US-5340825-A | Pro drugs for CCK antagonists | WARNER-LAMBERT COMPANY (US) | 1994-08-23 | — | — | US | disclosed |
| EP-0546108-A4 | PRO-DRUGS FOR CCK ANTAGONISTS | — | 1993-09-22 | — | — | EP | disclosed |
| EP-0546108-A1 | PRO-DRUGS FOR CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992004038-A1 | PRO-DRUGS FOR CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |