SCHEMBL895754

SCHEMBL895754

O=C(O)C1CCCCC1(Cl)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 6/20 0.34
CYP1A2 P05177 3/20 0.34
CYP2C19 P33261 3/20 0.34
GRM2 Q14416 2/20 0.34
GRM3 Q14832 2/20 0.34
ALOX15 P16050 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
GRM8 O00222 2/20 0.34
GRM6 O15303 2/20 0.34
LMNA P02545 2/20 0.34
GRM5 P41594 1/20 0.34
MTOR P42345 1/20 0.34
GRM1 Q13255 1/20 0.34
PLCB1 Q9NQ66 1/20 0.34
TSHR P16473 1/20 0.34
HSD11B1 P28845 2/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9006136 0.94 GRM4 (0.35) GRM4CYP1A2CYP2C19GRM2GRM3
SCHEMBL8452132 0.85 SLC1A2 (0.38) GRM4CYP1A2CYP2C19GRM2GRM3
SCHEMBL8008305 0.80 MAPT (0.40) CYP2C19HSD11B1SLC1A2SLC1A1HDAC8
SCHEMBL11819305 0.77 CYP2C19 (0.30) CYP2C19
SCHEMBL8363486 0.77 CYP2C19 (0.30) CYP2C19
SCHEMBL25218266 0.76 GRM4 (0.38) GRM4CYP1A2CYP2C19GRM2GRM3
SCHEMBL6025947 0.75 EPHX1 (0.33) CYP1A2LMNAPOLB
SCHEMBL38190 0.74 CYP2C19 (0.40) GRM4CYP1A2CYP2C19GRM2GRM3
SCHEMBL8018907 0.73 NPSR1 (0.35) SLC1A2SLC1A1
SCHEMBL19433874 0.73 HSD11B1 (0.37) GRM4CYP1A2CYP2C19GRM2GRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62267322-A None JP disclosed
CN-113583443-B Transparent polyimide applied to flexible photoelectric field and preparation method thereof 深圳瑞华泰薄膜科技股份有限公司 2022-11-22 CN disclosed
EP-2498136-B1 Intermediate transfer belt and image forming apparatus using the same RICOH CO LTD (JP) 2018-05-02 EP disclosed
US-8521073-B2 Intermediate transfer member and image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2013-08-27 US disclosed
US-20120230740-A1 INTERMEDIATE TRANSFER BELT AND IMAGE FORMING APPARATUS USING THE SAME RICOH COMPANY, LTD. (JP) 2012-09-13 US disclosed
EP-2498136-A1 Intermediate transfer belt and image forming apparatus using the same Ricoh Company, Ltd. (JP) 2012-09-12 EP disclosed
US-20120082488-A1 INTERMEDIATE TRANSFER MEMBER AND IMAGE FORMING APPARATUS USING THE SAME RICOH COMPANY, LTD. (JP) 2012-04-05 US disclosed
EP-1453675-B1 PHOTOSENSITIVE COMPOSITION AND PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE EASTMAN KODAK CO (US) 2009-10-07 EP disclosed
EP-1453675-A1 PHOTOSENSITIVE COMPOSITION AND PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE Kodak Polychrome Graphics Company Ltd. (US) 2004-09-08 EP disclosed
WO-2003051631-A1 PHOTOSENSITIVE COMPOSITION AND PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) 2003-06-26 WO disclosed
EP-0736561-A2 Dihydroxy compound mixtures and polymers thereof GENERAL ELECTRIC COMPANY (US) 1996-10-09 EP disclosed
EP-0452782-A1 Novel intermediates for preparing guanidine derivatives, their preparation and use Takeda Chemical Industries, Ltd. (JP) 1991-10-23 EP disclosed
EP-0249662-A1 Process for producing three-dimensionally crosslinked polyester having the liquid crystal structure Polyplastics Co., Ltd. (JP) 1987-12-23 EP disclosed
JP-S62267322-A PRODUCTION OF DIACETYLENE GROUP-CONTAINING POLYESTER AGENCY OF IND SCIENCE & TECHNOL 1987-11-20 JP disclosed
US-4414220-A HUPOGLYCEMIC, ANTIDIABETIC PFIZER INC. (US) 1983-11-08 US disclosed
US-4333932-A DIHYDROISOINDOLES, HYPOGLYCEMIC, ANTIDIABETIC PFIZER INC. (US) 1982-06-08 US disclosed
EP-0010896-B1 ORGANIC DIAMINE COMPOUNDS FOR USE AS ORAL HYPOGLYCEMIC AGENTS AND PHARMACEUTICAL COMPOSITIONS THEREOF PFIZER INC. (US) 1981-12-30 EP disclosed
US-4220650-A HYPOGLYCEMIC PFIZER INC. (US) 1980-09-02 US disclosed
EP-0010896-A1 Organic diamine compounds for use as oral hypoglycemic agents and pharmaceutical compositions thereof PFIZER INC. (US) 1980-05-14 EP disclosed
US-4070433-A Casting films of poly(meta-phenylene isophthalamide) and its copolymers UNITIKA LTD. (JA) 1978-01-24 US disclosed