Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957654 | 1.00 | ALDH1A1 (0.33) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL8957695 | 0.92 | ALDH1A1 (0.35) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL8957618 | 0.92 | — | — | |
| SCHEMBL8957702 | 0.91 | — | — | |
| SCHEMBL8957715 | 0.91 | ALDH1A1 (0.35) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL8957645 | 0.91 | ALDH1A1 (0.35) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL8957611 | 0.91 | — | — | |
| SCHEMBL8957603 | 0.89 | — | — | |
| SCHEMBL673035 | 0.89 | ALDH1A1 (0.38) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL8957750 | 0.77 | RORC (0.37) | ALDH1A1CYP3A4HPGDTSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556931-A | LENSES | TOKUYAMA CORPORATION (JP) | 1996-09-17 | — | — | US | claimed |
| US-5556931-A | LENSES | TOKUYAMA CORPORATION (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0691550-A2 | Polymerizable composition and organic glass | TOKUYAMA CORPORATION (JP) | 1996-01-10 | — | — | EP | disclosed |