SCHEMBL673035

SCHEMBL673035

C=C(C)C(=O)OC(C)Oc1c(Br)cc(C(C)(C)c2cc(Br)c(OC(C)OC(=O)C(=C)C)c(Br)c2)cc1Br

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
ALOX15 P16050 2/20 0.38
ALOX12 P18054 2/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
CASP1 P29466 1/20 0.38
RECQL P46063 1/20 0.38
HIF1A Q16665 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CHEK1 O14757 1/20 0.33
DAPK3 O43293 1/20 0.33
RET P07949 1/20 0.33
PDGFRB P09619 1/20 0.33
PIM1 P11309 1/20 0.33
PDGFRA P16234 1/20 0.33
KDR P35968 1/20 0.33
MAPK8 P45983 1/20 0.33
RPS6KA3 P51812 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8957695 0.93 ALDH1A1 (0.35) ALDH1A1ALOX15ALOX12CYP3A4HPGD
SCHEMBL8957645 0.92 ALDH1A1 (0.35) ALDH1A1ALOX15ALOX12CYP3A4HPGD
SCHEMBL8957715 0.92 ALDH1A1 (0.35) ALDH1A1ALOX15ALOX12CYP3A4HPGD
SCHEMBL8957680 0.89 ALDH1A1 (0.33) ALDH1A1ALOX15ALOX12CYP3A4HPGD
SCHEMBL8957654 0.89 ALDH1A1 (0.33) ALDH1A1ALOX15ALOX12CYP3A4HPGD
SCHEMBL3413335 0.85 HSD17B10 (0.38) ALDH1A1ALOX15ALOX12TSHRHSD17B10
SCHEMBL8957603 0.83
SCHEMBL8957623 0.83 ALOX15 (0.35) ALDH1A1ALOX15ALOX12CYP3A4HPGD
SCHEMBL8957698 0.82 ALDH1A1 (0.36) ALDH1A1ALOX15ALOX12CYP3A4HPGD
SCHEMBL6993149 0.81 ALDH1A1 (0.38) ALDH1A1ALOX15ALOX12CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160185887-A1 POLYMERIZABLE COMPOSITION FOR HIGH-REFRACTIVE OPTICAL MATERIAL AND METHOD FOR PREPARING HIGH-REFRACTIVE OPTICAL MATERIAL KOC SOLUTION CO., LTD. (KR) 2016-06-30 US claimed
US-8529789-B2 Curable composition TOKUYAMA CORPORATION (JP) 2013-09-10 US claimed
US-5910516-A PHOTOPOLYMERIZING AN UNSATURATED COMPOUND, AN ULTRAVIOLET PHOTOINITIATOR AND A PHOTOCHROMIC COMPOUND; USING A FILTER WHICH ELIMINATES THE UV LIGHT OF WAVELENGTH SHORTER THAN 400 NM. TOKUYAMA CORPORATION (JP) 1999-06-08 US claimed
US-5556931-A LENSES TOKUYAMA CORPORATION (JP) 1996-09-17 US claimed
JP-58072101-A None JP disclosed
JP-57054901-A None JP disclosed
JP-7109318-A None JP disclosed
US-20260140398-A1 OPTICAL MATERIAL COMPOSITION, CURED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2026-05-21 US disclosed
EP-3901185-B1 CURABLE COMPOSITION FOR OPTICAL MATERIALS, AND OPTICAL MATERIAL TOKUYAMA CORP (JP) 2026-03-25 EP disclosed
EP-4696722-A1 (METH)ACRYLATE, CURABLE COMPOSITION, CURED BODY, LAMINATE, OPTICAL ARTICLE, LENS, AND EYEGLASSES TOKUYAMA CORPORATION (JP) 2026-02-18 EP disclosed
US-12552745-B2 Compound for optical materials, curable composition, cured body, and optical article TOKUYAMA CORPORATION (JP) 2026-02-17 US disclosed
EP-3779572-B1 OPTICAL ARTICLE HOYA LENS THAILAND LTD (TH) 2025-11-19 EP disclosed
EP-0518687-A1 Primer layer for plastic lenses NIPPON SHEET GLASS CO., LTD. (JP) 1992-12-16 EP disclosed
EP-0500346-A2 Process for producing plastic lens NIPPON SHEET GLASS CO., LTD. (JP) 1992-08-26 EP disclosed
EP-0449669-A1 Photochromic compound, composition and use thereof TOKUYAMA CORPORATION (JP) 1991-10-02 EP disclosed
US-5026618-A Photosensitive material and volume type phase hologram member formed therefrom CANON KABUSHIKI KAISHA (JP) 1991-06-25 US disclosed
US-5015523-A Coated synthetic resin lens SEIKO EPSON CORPORATION (JP) 1991-05-14 US disclosed
US-4931521-A Optical materials composed of resin from thioacrylat esters NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1990-06-05 US disclosed
JP-S5872101-A PLASTIC LENS SEIKO EPSON CORP 1983-04-30 JP disclosed
JP-S5754901-A SYNTHETIC RESIN LENS SEIKO EPSON CORP 1982-04-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552745-B2 Compound for optical materials, curable composition, cured body, and optical article C5, SCO2, ZYX ALDH1A1 1308/4885ALOX15 642/4885ALOX12 336/4885
US-20260140398-A1 OPTICAL MATERIAL COMPOSITION, CURED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES CRYAA, FEM1B, MAPRE1 ALDH1A1 588/4885ALOX15 125/4885ALOX12 160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.