Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957684 | 0.88 | ALDH1A1 (0.37) | ALDH1A1THRBTHRA | |
| SCHEMBL8957658 | 0.88 | ALDH1A1 (0.37) | ALDH1A1THRBTHRA | |
| SCHEMBL8957622 | 0.88 | ALDH1A1 (0.33) | ALDH1A1AR | |
| SCHEMBL1468098 | 0.81 | AR (0.46) | ALDH1A1HIF1AHSD17B10TDP1AR | |
| SCHEMBL14173194 | 0.80 | ALDH1A1 (0.47) | ALDH1A1THRBTHRACYP3A4HPGD | |
| SCHEMBL8957757 | 0.79 | CYP2C19 (0.42) | AR | |
| SCHEMBL5350567 | 0.77 | ALDH1A1 (0.49) | ALDH1A1THRBTHRACYP3A4HPGD | |
| SCHEMBL5223398 | 0.77 | AR (0.43) | ALDH1A1CYP3A4HPGDTSHRHIF1A | |
| SCHEMBL21842534 | 0.76 | ALDH1A1 (0.43) | ALDH1A1THRBTHRACYP3A4HPGD | |
| SCHEMBL7897872 | 0.76 | ALDH1A1 (0.34) | ALDH1A1THRBTHRATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556931-A | LENSES | TOKUYAMA CORPORATION (JP) | 1996-09-17 | — | — | US | claimed |
| US-5556931-A | LENSES | TOKUYAMA CORPORATION (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0691550-A2 | Polymerizable composition and organic glass | TOKUYAMA CORPORATION (JP) | 1996-01-10 | — | — | EP | disclosed |