Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30340743 | 0.80 | THRB (0.38) | THRATHRBTSHRHSD17B10MAPT | |
| SCHEMBL1837592 | 0.79 | HSD17B10 (0.37) | ALDH1A1HSD17B10MAPTPTGDR2 | |
| SCHEMBL8957697 | 0.76 | ALDH1A1 (0.46) | ALDH1A1THRATHRBTSHRHSD17B10 | |
| SCHEMBL10604795 | 0.74 | HSD17B10 (0.36) | ALDH1A1THRATHRBTSHRHSD17B10 | |
| SCHEMBL11173040 | 0.71 | ALDH1A1 (0.33) | ALDH1A1THRATHRBTSHR | |
| SCHEMBL9807440 | 0.71 | ALDH1A1 (0.66) | ALDH1A1TSHRMAPT | |
| SCHEMBL7620486 | 0.71 | HSD17B10 (0.37) | ALDH1A1HSD17B10MAPTPTGDR2 | |
| SCHEMBL10607457 | 0.70 | TSHR (0.46) | THRATHRBTSHRHSD17B10MAPT | |
| SCHEMBL1893078 | 0.70 | MTNR1A (0.38) | THRATHRB | |
| SCHEMBL14173194 | 0.70 | ALDH1A1 (0.47) | ALDH1A1THRATHRBTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184323-B1 | FOR OPHTHALMIC LENSES | ESSILOR INTERNATIONAL-COMPAGNIE GENERALE D'OPTIQUE (FR) | 2001-02-06 | — | — | US | disclosed |