SCHEMBL895784

SCHEMBL895784

Cc1cc2oc3ccccc3cc-2c(=O)c1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.49
MEN1 O00255 4/20 0.49
POLB P06746 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
CTDSP1 Q9GZU7 1/20 0.49
RAB9A P51151 5/20 0.47
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 3/20 0.46
MAOB P27338 2/20 0.46
MAOA P21397 1/20 0.46
GLA P06280 1/20 0.44
MAPT P10636 2/20 0.44
TP53 P04637 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
PTPRC P08575 1/20 0.43
PTPN1 P18031 1/20 0.43
NPC1 O15118 4/20 0.43
SIRT2 Q8IXJ6 1/20 0.42
SIRT1 Q96EB6 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9160537 0.82 RAB9A (0.47) KMT2AMEN1POLBTDP1CTDSP1
SCHEMBL9803154 0.80 ADORA3 (0.36) KMT2AMEN1POLBTDP1CTDSP1
SCHEMBL26098724 0.79 KMT2A (0.50) KMT2AMEN1POLBTDP1CTDSP1
SCHEMBL27278538 0.79 KMT2A (0.48) KMT2AMEN1POLBTDP1CTDSP1
SCHEMBL6891938 0.75 KMT2A (0.48) KMT2AMEN1POLBTDP1CTDSP1
SCHEMBL30417366 0.74 RAB9A (0.68) KMT2AMEN1POLBRAB9AALDH1A1
SCHEMBL18984965 0.74 MAOB (0.62) KMT2AMEN1POLBTDP1CTDSP1
SCHEMBL8596566 0.73 PTPRC (0.46) KMT2AMEN1POLBRAB9AALDH1A1
SCHEMBL11672616 0.73 MAOB (0.56) KMT2AMEN1POLBTDP1CTDSP1
SCHEMBL9467872 0.72 KDM4E (0.47) POLBRAB9AALDH1A1KDM4EMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8793078-B2 Method for predicting activation energy using atomic fingerprint descriptor or atomic descriptor BIOINFORMATICS & MOLECULAR DESIGN RESEARCH CENTER (KR) 2014-07-29 US disclosed
US-20120084012-A1 METHOD FOR PREDICTING ACTIVATION ENERGY USING ATOMIC FINGERPRINT DESCRIPTOR OR ATOMIC DESCRIPTOR BIOINFORMATICS & MOLECULAR DESIGN RESEARCH CENTER (KR) 2012-04-05 US disclosed
US-20110213558-A1 METHOD FOR PREDICTING ACTIVATION ENERGY USING AN ATOMIC FINGERPRINT DESCRIPTOR OR AN ATOMIC DESCRIPTOR BIOINFORMATICS & MOLECULAR DESIGN RESEARCH CENTER (KR) 2011-09-01 US disclosed
EP-2354987-A2 METHOD FOR PREDICTING ACTIVATION ENERGY USING AN ATOMIC FINGERPRINT DESCRIPTOR OR AN ATOMIC DESCRIPTOR Bioinformatics&Molecular Design Research Center (KR) 2011-08-10 EP disclosed
WO-2010056053-A2 METHOD FOR PREDICTING ACTIVATION ENERGY USING AN ATOMIC FINGERPRINT DESCRIPTOR OR AN ATOMIC DESCRIPTOR 사단법인 분자설계연구소 (KR) 2010-05-20 WO disclosed
EP-0198798-B1 LIGHT-SENSITIVE POLYCONDENSATES, PROCESS FOR THEIR PREPARATION, MATERIALS COATED THEREWITH AND THEIR USE CIBA-GEIGY AG (CH) 1991-05-29 EP disclosed
EP-0198798-A2 Light-sensitive polycondensates, process for their preparation, materials coated therewith and their use CIBA-GEIGY AG (CH) 1986-10-22 EP disclosed