Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871210 | 0.81 | P2RX4 (0.33) | ALDH1A1 | |
| SCHEMBL11786779 | 0.78 | ALDH1A1 (0.34) | ALDH1A1TSHR | |
| SCHEMBL196002 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL584108 | 0.73 | TP53 (0.35) | — | |
| SCHEMBL7078801 | 0.71 | ALOX5 (0.34) | — | |
| SCHEMBL24117676 | 0.69 | SLC7A5 (0.32) | — | |
| SCHEMBL156098 | 0.69 | TDP1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL8439081 | 0.67 | P2RX4 (0.33) | ALDH1A1 | |
| SCHEMBL14036959 | 0.67 | — | — | |
| SCHEMBL5686235 | 0.67 | TDP1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103087022-B | Oxalyl-substituted-3-aryltetronate compounds, and preparations and applications thereof | UNIV NANKAI | 2015-06-10 | — | — | CN | disclosed |
| CN-103087022-A | Oxalyl-substituted-3-aryltetronate compounds, and preparations and applications thereof | UNIV NANKAI | 2013-05-08 | — | — | CN | disclosed |
| EP-0469889-B1 | (p-Carbonylaminophenyl)-sulphonyl-nitromethane derivatives | ZENECA LTD (GB) | 1996-01-17 | — | — | EP | disclosed |
| US-5189031-A | Inhibitor of enzyme aldose reductase, useful in the treatment of certain peripheral effects of diabetes and galactosemia | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-23 | — | — | US | disclosed |
| US-5110808-A | Aldose reductase inhibitors; peripheral effects of diabetes and galactosemia | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1992-05-05 | — | — | US | disclosed |
| EP-0469889-A1 | (p-Carbonylaminophenyl)-sulphonyl-nitromethane derivatives | ZENECA LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |