Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetonitrile SCHEMBL15167963 | 0.87 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL8597550 | 0.75 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL8958069 | 0.75 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL11332824 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TSHRTP53 | |
| SCHEMBL10871210 | 0.72 | P2RX4 (0.33) | ALDH1A1P2RX4P2RX1P2RX3P2RX7 | |
| SCHEMBL8439081 | 0.72 | P2RX4 (0.33) | ALDH1A1P2RX4P2RX1P2RX3P2RX7 | |
| SCHEMBL329195 | 0.71 | TSHR (0.36) | ALDH1A1TSHR | |
| SCHEMBL11786779 | 0.71 | ALDH1A1 (0.34) | ALDH1A1TSHR | |
| SCHEMBL11559481 | 0.71 | — | — | |
| SCHEMBL2894127 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 491 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675790-B1 | SUBSTITUTED 1, 2, 3, 4-TETRAHYDROQUINOLIN-7-YL CARBAMATES AS ACETYLCHOLINESTERASE INHIBITORS FOR TREATMENT OF ALZHEIMER'S DISEASE | COUNCIL SCIENT IND RES (IN) | 2015-11-18 | — | — | EP | claimed |
| US-8946261-B2 | Substituted 1, 2, 3, 4-tetrahydroquinolin-7-yl carbamates as acetylcholinesterase inhibitors for treatment of Alzheimer's disease | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-02-03 | — | — | US | claimed |
| EP-2675790-A1 | SUBSTITUTED 1, 2, 3, 4-TETRAHYDROQUINOLIN-7-YL CARBAMATES AS ACETYLCHOLINESTERASE INHIBITORS FOR TREATMENT OF ALZHEIMER'S DISEASE | Council of Scientific & Industrial Research (IN) | 2013-12-25 | — | — | EP | claimed |
| US-20130324573-A1 | SUBSTITUTED 1, 2, 3, 4-TETRAHYDROQUINOLIN-7-YL CARBAMATES AS ACETYLCHOLINESTERASE INHIBITORS FOR TREATMENT OF ALZHEIMER'S DISEASE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-12-05 | — | — | US | claimed |
| WO-2012111021-A1 | SUBSTITUTED 1, 2, 3, 4-TETRAHYDROQUINOLIN-7-YL CARBAMATES AS ACETYLCHOLINESTERASE INHIBITORS FOR TREATMENT OF ALZHEIMER'S DISEASE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGISTRATION OF SOCIETIES ACT (ACT XXI OF 1860) (IN) | 2012-08-23 | — | — | WO | claimed |
| JP-8134046-A | — | — | None | — | — | JP | disclosed |
| US-20260102501-A1 | ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS | NUVATION BIO INC (US) | 2026-04-16 | — | — | US | disclosed |
| US-20250346612-A1 | INTRAMOLECULAR CYCLIZATION FOR GENERAL SYNTHESIS OF BICYCLIC ALKYL BIOISOSTERE BORONATES | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-11-13 | — | — | US | disclosed |
| WO-2025229046-A1 | SUBSTITUTED HYDROQUINOLINES FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME | MOLIUS SAGLIK TEKNOLOJILERI ANONIM SIRKETI (TR) | 2025-11-06 | — | — | WO | disclosed |
| EP-4644375-A1 | SUBSTITUTED HYDROQUINOLINES FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME | Molius Saglik Teknolojileri Anonim Sirketi (TR) | 2025-11-05 | — | — | EP | disclosed |
| US-12410136-B2 | Pyridinyl morpholine compound, preparation method therefor, and application thereof | SHANGHAI ZHONGZE THERAPEUTICS, CO. LTD. (CN) | 2025-09-09 | — | — | US | disclosed |
| EP-4593824-A2 | ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS | Nuvation Bio Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| US-4451467-A | HYPOTENSIVE AGENTS | Ishikawa, Masayuki (JP) | 1984-05-29 | — | — | US | disclosed |
| EP-0101023-A1 | Process for preparing 2-carbamoyloxyalkyl-1,4-dihydropyridine derivatives and intermediates useful for the process | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1984-02-22 | — | — | EP | disclosed |
| EP-0056637-A1 | 4(3H)-quinazolinone derivatives, process for production thereof and pharmaceutical compositions comprising said compounds | Ishikawa, Masayuki (JP) | 1982-07-28 | — | — | EP | disclosed |
| US-4203988-A | ANTISECRETORY AGENTS | MERCK & CO., INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4101571-A | REACTING SULFAMIC ACIDS WITH PHOSGENE | BASF AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |
| US-4051252-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3989710-A | POSTEMERGENCE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |
| US-3986973-A | CYANOFORMATES AND CYANOFORMAMIDES AS BLEACH ACTIVATORS | AMERICAN CYANAMID COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346612-A1 | INTRAMOLECULAR CYCLIZATION FOR GENERAL SYNTHESIS OF BICYCLIC ALKYL BIOISOSTERE BORONATES | LSS, PAICS, BLVRB | ALDH1A1 2342/4885TSHR 1400/4885P2RX4 4491/4885 |
| US-20130324573-A1 | SUBSTITUTED 1, 2, 3, 4-TETRAHYDROQUINOLIN-7-YL CARBAMATES AS ACETYLCHOLINESTERASE INHIBITORS FOR TREATMENT OF ALZHEIMER'S DISEASE | ACHE, BCHE, CHAT | ALDH1A1 1202/4885TSHR 3352/4885P2RX4 2198/4885 |
| US-20260102501-A1 | ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS | NR5A1, NR5A2, NR3C1 | ALDH1A1 3672/4885TSHR 40/4885P2RX4 4638/4885 |
| US-12410136-B2 | Pyridinyl morpholine compound, preparation method therefor, and application thereof | HTR2C, HTR3D, HTR5A | ALDH1A1 1288/4885TSHR 681/4885P2RX4 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.