Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958254 | 1.00 | GRM2 (0.38) | GRM2GRM3EPHX1ALOX5ALDH1A1 | |
| SCHEMBL8958245 | 1.00 | GRM2 (0.38) | GRM2GRM3EPHX1ALOX5ALDH1A1 | |
| SCHEMBL1410686 | 0.84 | GRM2 (0.50) | GRM2GRM3EPHX1ALDH1A1MEN1 | |
| SCHEMBL27921295 | 0.78 | GRM2 (0.37) | GRM2GRM3EPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5197125 | 0.78 | EPHX1 (0.38) | GRM2GRM3EPHX1ALOX5ALDH1A1 | |
| SCHEMBL664691 | 0.76 | EPHX1 (0.33) | GRM2GRM3EPHX1ALOX5ALDH1A1 | |
| SCHEMBL27576640 | 0.73 | SMN1; SMN2 (0.33) | EPHX1ALOX5ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14920977 | 0.73 | EPHX1 (0.33) | EPHX1ALOX5ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28052590 | 0.73 | ARG1 (0.43) | GRM2GRM3EPHX1ALDH1A1MEN1 | |
| SCHEMBL664453 | 0.73 | EPHX2 (0.34) | EPHX1ALOX5ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559233-A | 3-/P-PHENYLBENZYL/IMIDAZOLONES AND PYRIMIDONES | SANOFI (FR) | 1996-09-24 | — | — | US | disclosed |
| US-5352788-A | Angiotensin antagonist | ELF SANOFI (FR) | 1994-10-04 | — | — | US | disclosed |
| US-5270317-A | N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1993-12-14 | — | — | US | disclosed |