Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.50 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.50 |
| ▸ | ARG1 | P05089 | 3/20 | 0.38 |
| ▸ | ARG2 | P78540 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325583 | 0.90 | GRM2 (0.55) | GRM2GRM3ARG1ARG2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL21239443 | 0.88 | GRM2 (0.53) | GRM2GRM3ARG1ARG2ALDH1A1 | |
| SCHEMBL28052590 | 0.85 | ARG1 (0.43) | GRM2GRM3ARG1ARG2ALDH1A1 | |
| SCHEMBL8958248 | 0.84 | GRM2 (0.38) | GRM2GRM3ALDH1A1MEN1CYP1A2 | |
| SCHEMBL8958254 | 0.84 | GRM2 (0.38) | GRM2GRM3ALDH1A1MEN1CYP1A2 | |
| SCHEMBL8958245 | 0.84 | GRM2 (0.38) | GRM2GRM3ALDH1A1MEN1CYP1A2 | |
| SCHEMBL4619823 | 0.82 | GRM2 (0.45) | GRM2GRM3ARG1ARG2ALDH1A1 | |
| SCHEMBL27921295 | 0.78 | GRM2 (0.37) | GRM2GRM3ALDH1A1THRBRECQL | |
| SCHEMBL8735978 | 0.77 | KEAP1 (0.37) | GRM2GRM3ALDH1A1MEN1CYP1A2 | |
| SCHEMBL5568695 | 0.77 | RECQL (0.39) | GRM2GRM3ALDH1A1CYP1A2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295410-A1 | HDAC inhibitor | Chroma Therapeutics Limited (GB) | 2011-03-16 | — | — | EP | disclosed |