SCHEMBL8958491

SCHEMBL8958491

O=S(=O)(O)c1ccccc1-c1ccccc1Pc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PGAM1 P18669 1/20 0.35
MYC P01106 1/20 0.34
CHAT P28329 1/20 0.34
SNCA P37840 1/20 0.34
TTR P02766 2/20 0.33
FABP4 P15090 1/20 0.33
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
MAPK14 Q16539 1/20 0.33
NR4A1 P22736 1/20 0.33
NSD2 O96028 2/20 0.32
CASP6 P55212 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
KDM4A O75164 1/20 0.32
USP2 O75604 1/20 0.32
ALPL P05186 1/20 0.32
PLCG1 P19174 1/20 0.32
TNNI3 P19429 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30035563 0.85 TSHR (0.41) TSHRSMN1; SMN2PGAM1MYCCHAT
SCHEMBL2593805 0.85 TSHR (0.41) TSHRSMN1; SMN2PGAM1MYCCHAT
SCHEMBL8818051 0.81 TSHR (0.38) TSHRSMN1; SMN2MYCCHATSNCA
SCHEMBL4061116 0.79 CA12 (0.32) TDP1CA12CA9
SCHEMBL458284 0.79 SMN1; SMN2 (0.48) TSHRSMN1; SMN2PGAM1MYCCHAT
SCHEMBL28837581 0.77 SMN1; SMN2 (0.46) TSHRSMN1; SMN2PGAM1MYCCHAT
SCHEMBL27451836 0.76 MMP2 (0.40) TSHRSMN1; SMN2MYCMMP14ALDH1A1
SCHEMBL9395091 0.76 PGAM1 (0.36) TSHRSMN1; SMN2PGAM1MYCCHAT
SCHEMBL8721692 0.73 TSHR (0.43) TSHRSMN1; SMN2SNCANSD2CASP6
SCHEMBL10951322 0.73 MYC (0.42) TSHRSMN1; SMN2PGAM1MYCCHAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5488096-A Copolymers of carbon monoxide and an olefinically unsaturated compound and process for the preparation thereof SHELL OIL COMPANY (US) 1996-01-30 US claimed