Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL944147 | 0.80 | GABRA1 (0.54) | GABRA1GABRB2MEN1KMT2AALDH1A1 | |
| O-Xylene SCHEMBL28101428 | 0.74 | DNM1 (0.55) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Octadecylamine SCHEMBL29155792 | 0.73 | DNM1 (0.59) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL1018021 | 0.73 | GABRA1 (0.79) | GABRA1GABRB2MEN1KMT2AALDH1A1 | |
| SCHEMBL15589311 | 0.72 | GABRA1 (0.46) | GABRA1GABRB2MEN1KMT2AALDH1A1 | |
| Dodecylamine SCHEMBL11314986 | 0.71 | DNM1 (0.61) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL23505621 | 0.71 | KEAP1 (0.33) | — | |
| SCHEMBL18244912 | 0.69 | GABRA1 (0.67) | GABRA1GABRB2 | |
| SCHEMBL1457069 | 0.68 | GABRA1 (0.50) | GABRA1GABRB2MEN1KMT2AALDH1A1 | |
| Dodecylamine SCHEMBL8912921 | 0.68 | DNM1 (0.46) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469889-B1 | (p-Carbonylaminophenyl)-sulphonyl-nitromethane derivatives | ZENECA LTD (GB) | 1996-01-17 | — | — | EP | disclosed |
| EP-0469887-B1 | Acetamide derivatives | ZENECA LTD (GB) | 1994-12-14 | — | — | EP | disclosed |
| EP-0469888-B1 | Amidobenzenes | ICI PLC (GB) | 1994-09-28 | — | — | EP | disclosed |
| EP-0469887-A1 | Acetamide derivatives | ZENECA LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| EP-0469888-A1 | Amidobenzenes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-05 | — | — | EP | disclosed |
| EP-0469889-A1 | (p-Carbonylaminophenyl)-sulphonyl-nitromethane derivatives | ZENECA LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |