Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IL2 | P60568 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004285 | 0.86 | HRH3 (0.42) | HRH3KDM4ELMNACYP2D6HTT | |
| SCHEMBL8958463 | 0.85 | HRH3 (0.38) | HRH3KDM4ELMNACYP2D6HTT | |
| SCHEMBL8958413 | 0.80 | HRH3 (0.34) | HRH3KDM4ELMNACYP2D6 | |
| SCHEMBL8958653 | 0.79 | CREBBP (0.37) | HRH3KDM4ECYP2D6 | |
| SCHEMBL7934334 | 0.78 | KDM4E (0.45) | HRH3KDM4ELMNAHTTATM | |
| SCHEMBL7112634 | 0.77 | KDM4E (0.53) | HRH3KDM4ELMNACYP2D6HTT | |
| SCHEMBL8958470 | 0.77 | KDM4E (0.40) | HRH3KDM4ELMNACYP2D6HTT | |
| SCHEMBL7009195 | 0.77 | HRH3 (0.42) | HRH3KDM4ELMNACYP2D6HTT | |
| SCHEMBL10835648 | 0.75 | KDM4E (0.50) | HRH3KDM4ELMNACYP2D6HTT | |
| Hydrochloric Acid SCHEMBL9308089 | 0.74 | HRH3 (0.42) | HRH3KDM4ELMNACYP2D6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |