Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958413 | 0.97 | HRH3 (0.34) | CREBBPEP300KDM4CICAM1SELE | |
| SCHEMBL7004715 | 0.89 | ICAM1 (0.36) | CREBBPEP300KDM4CICAM1SELE | |
| SCHEMBL7093547 | 0.86 | HRH3 (0.36) | CREBBPEP300KDM4CICAM1SELE | |
| SCHEMBL8958463 | 0.77 | HRH3 (0.38) | HRH3KDM4ECYP2D6 | |
| SCHEMBL8873345 | 0.73 | MEN1 (0.36) | HRH3OXTRAVPR1A | |
| SCHEMBL92954 | 0.72 | NAAA (0.47) | CREBBPEP300KDM4COXTRAVPR1A | |
| SCHEMBL7934334 | 0.70 | KDM4E (0.45) | HRH3KDM4E | |
| SCHEMBL7112634 | 0.69 | KDM4E (0.53) | HRH3KDM4ECYP2D6 | |
| SCHEMBL4184332 | 0.69 | KDM4C (0.47) | CREBBPEP300KDM4CICAM1SELE | |
| SCHEMBL7937331 | 0.69 | FABP4 (0.42) | HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |