Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.42 |
| ▸ | NOS2 | P35228 | 4/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922736 | 1.00 | NOS1 (0.42) | NOS1NOS2NOS3KDM4EALDH1A1 | |
| SCHEMBL13560831 | 0.75 | CTDSP1 (0.42) | NOS1NOS2NOS3KDM4EALDH1A1 | |
| SCHEMBL4039458 | 0.75 | NOS3 (0.37) | NOS1NOS2NOS3KDM4EALDH1A1 | |
| SCHEMBL9860940 | 0.75 | NOS3 (0.37) | NOS1NOS2NOS3KDM4EALDH1A1 | |
| SCHEMBL14246443 | 0.75 | NOS1 (0.46) | NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL4039461 | 0.75 | NOS3 (0.37) | NOS1NOS2NOS3KDM4EALDH1A1 | |
| SCHEMBL27427946 | 0.75 | KDM4E (0.37) | NOS1NOS2NOS3KDM4EALDH1A1 | |
| SCHEMBL17816554 | 0.73 | NOS1 (0.36) | NOS1NOS2NOS3 | |
| SCHEMBL1133545 | 0.72 | NOS1 (0.52) | NOS1NOS2NOS3 | |
| SCHEMBL13576632 | 0.72 | NOS1 (0.47) | NOS1NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8059567-A | — | — | None | — | — | JP | disclosed |
| JP-8059568-A | — | — | None | — | — | JP | disclosed |
| CN-1105706-C | Cyclic amidino formulations useful as nitric oxide synthase inhibitors | SEARLE & CO (US) | 2003-04-16 | — | — | CN | disclosed |
| CN-1077886-C | Amidino derivatives useful as nitric oxide synthase inhibitors | SEARLE & CO (US) | 2002-01-16 | — | — | CN | disclosed |
| CN-1137268-A | Amidino derivatives useful as nitric oxide synthase inhibitors | SEARLE & CO (US) | 1996-12-04 | — | — | CN | disclosed |
| JP-H0859567-A | PRODUCTION OF TRANS-4-ALKYLCYCLOHEXYLAMINE | NIPPON KASEI CHEM CO LTD | 1996-03-05 | — | — | JP | disclosed |
| JP-H0859568-A | PRODUCTION OF TRANS-4-ALKYLCYCLOHEXYLAMINE | NIPPON KASEI CHEM CO LTD | 1996-03-05 | — | — | JP | disclosed |
| US-4395413-A | NICOTINE ANTIALLERGEN, ANESTHETIC, ANALGESIC, HYPOTENSIVE, AND ANTIULCER AGENT | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1983-07-26 | — | — | US | disclosed |