Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958675 | 1.00 | MAPT (0.49) | MAPTPDE7AS1PR4ALDH1A1LMNA | |
| SCHEMBL7172094 | 0.85 | THRA (0.42) | MAPTALDH1A1LMNAHPGDPDK1 | |
| SCHEMBL7690017 | 0.85 | THRA (0.39) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL7690021 | 0.85 | THRA (0.39) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL7172091 | 0.85 | THRA (0.42) | MAPTALDH1A1LMNAHPGDPDK1 | |
| SCHEMBL8923686 | 0.83 | PDK1 (0.51) | MAPTALDH1A1LMNAHPGDPDK1 | |
| SCHEMBL8923694 | 0.83 | PDK1 (0.51) | MAPTALDH1A1LMNAHPGDPDK1 | |
| SCHEMBL8924063 | 0.82 | PLA2G4B (0.59) | PDK1THRATHRBPLA2G4BTSHR | |
| SCHEMBL7692420 | 0.82 | PLA2G4B (0.59) | PDK1THRATHRBPLA2G4BTSHR | |
| SCHEMBL7692418 | 0.82 | PLA2G4B (0.59) | PDK1THRATHRBPLA2G4BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543078-A | A CHIRAL NONRACEMIC COMPOUND | UNIVERSITY RESEARCH CORPORATION (US) | 1996-08-06 | — | — | US | disclosed |