SCHEMBL9459574

SCHEMBL9459574

Fc1cc(F)cc(Oc2ccc(OCCCBr)c(Cl)c2)c1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 17/20 0.48
PPARG P37231 7/20 0.48
PPARD Q03181 11/20 0.47
S1PR4 O95977 1/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
HTR2A P28223 1/20 0.36
SLC6A4 P31645 1/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7079486 0.90 PPARA (0.58) PPARAPPARGPPARDHTR2ASLC6A4
SCHEMBL8959080 0.84 PPARA (0.46) PPARAPPARGPPARDHTR2ASLC6A4
SCHEMBL7079111 0.82 PPARA (0.48) PPARAPPARGPPARD
SCHEMBL9471654 0.81 PPARA (0.46) PPARAPPARGPPARDHTR2ASLC6A4
SCHEMBL9459506 0.80 PPARD (0.44) PPARAPPARGPPARDS1PR4FFAR1
SCHEMBL9723110 0.80 LTA4H (0.42) FFAR1FFAR4
SCHEMBL9470988 0.79 PPARA (0.46) PPARAPPARGPPARDFFAR1FFAR4
SCHEMBL9470975 0.78 PPARA (0.44) PPARAPPARGPPARDFFAR1FFAR4
SCHEMBL9470982 0.78 PPARA (0.44) PPARAPPARGPPARDFFAR1FFAR4
SCHEMBL8536866 0.77 MAPT (0.51) PPARAS1PR4HTR2ASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5216009-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-01 US disclosed
EP-0512557-A1 A method for controlling insect pests which belong to homoptera SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-11 EP disclosed