SCHEMBL8959162

SCHEMBL8959162

CCCOCc1ccc(OCCN)c(Cl)c1

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 4/20 0.66
SMN1; SMN2 Q16637 3/20 0.59
GLA P06280 1/20 0.59
ATM Q13315 1/20 0.49
BACE1 P56817 1/20 0.47
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
NPC1 O15118 1/20 0.42
TP53 P04637 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
RAB9A P51151 1/20 0.42
LMNA P02545 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8958937 0.82 CSNK2A1 (0.51) CSNK2A1SMN1; SMN2GLAATMBACE1
SCHEMBL8959111 0.78 SMN1; SMN2 (0.74) CSNK2A1SMN1; SMN2GLAATMBACE1
SCHEMBL12885103 0.77 IDO1 (0.55) CSNK2A1SMN1; SMN2NPC1TSHRRAB9A
SCHEMBL19602415 0.76 CSNK2A1 (0.75) CSNK2A1SMN1; SMN2GLAATMBACE1
SCHEMBL8959123 0.75 CSNK2A1 (0.55) CSNK2A1SMN1; SMN2GLABACE1
SCHEMBL14037664 0.74 CSNK2A1 (0.73) CSNK2A1SMN1; SMN2GLAATMBACE1
SCHEMBL8958965 0.73 KMT2A (0.48) CSNK2A1SMN1; SMN2ATMMEN1KMT2A
SCHEMBL3718885 0.73 CSNK2A1 (0.71) CSNK2A1SMN1; SMN2GLAATMBACE1
SCHEMBL3727357 0.73 CSNK2A1 (0.71) CSNK2A1SMN1; SMN2GLAATMBACE1
SCHEMBL10977759 0.73 CSNK2A1 (0.65) CSNK2A1SMN1; SMN2GLAATMBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed