SCHEMBL8958965

SCHEMBL8958965

CCCOCc1ccc(OCCNC(=O)C2CC2)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.48
MEN1 O00255 5/20 0.48
ATM Q13315 1/20 0.47
CNR1 P21554 2/20 0.45
CNR2 P34972 2/20 0.45
CSNK2A1 P68400 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
ALDH1A1 P00352 1/20 0.43
PKM P14618 3/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 2/20 0.41
MTNR1A P48039 1/20 0.41
CYP3A4 P08684 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
EPHX2 P34913 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959095 0.87 KMT2A (0.43) KMT2AMEN1ATMCNR1CNR2
SCHEMBL8959097 0.87 KMT2A (0.42) KMT2AMEN1ATMCNR1CNR2
SCHEMBL8959072 0.84 CNR1 (0.57) KMT2AMEN1ATMCNR1CNR2
SCHEMBL8959043 0.83 KMT2A (0.46) KMT2AMEN1ATMCNR1CNR2
SCHEMBL8959057 0.80 LTA4H (0.52) KMT2AMEN1ATMSMN1; SMN2ALDH1A1
SCHEMBL8959129 0.76 KMT2A (0.49) KMT2AMEN1SMN1; SMN2ALDH1A1PKM
SCHEMBL8959018 0.76 KMT2A (0.48) KMT2AMEN1CNR1CNR2SMN1; SMN2
SCHEMBL8959189 0.73 PKM (0.56) KMT2AMEN1SMN1; SMN2PKMNPC1
SCHEMBL8959162 0.73 CSNK2A1 (0.66) KMT2AMEN1ATMCSNK2A1SMN1; SMN2
SCHEMBL8959066 0.72 KMT2A (0.53) KMT2AMEN1SMN1; SMN2ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed