SCHEMBL8958937

SCHEMBL8958937

CCC(C)COCc1ccc(OCCN)c(Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 4/20 0.51
SMN1; SMN2 Q16637 3/20 0.50
GLA P06280 1/20 0.50
ATM Q13315 1/20 0.42
LMNA P02545 2/20 0.40
TP53 P04637 2/20 0.40
BACE1 P56817 1/20 0.40
PDK2 Q15119 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959162 0.82 CSNK2A1 (0.66) CSNK2A1SMN1; SMN2GLAATMLMNA
SCHEMBL8959097 0.76 KMT2A (0.42) SMN1; SMN2ATMPDK2MEN1NPC1
SCHEMBL8959153 0.70 GLA (0.48) CSNK2A1SMN1; SMN2GLABACE1HPGD
SCHEMBL8959111 0.70 SMN1; SMN2 (0.74) CSNK2A1SMN1; SMN2GLAATMTP53
SCHEMBL9119360 0.70 MRGPRX4 (0.48) SMN1; SMN2LMNATP53PDK2MRGPRX4
SCHEMBL8959123 0.70 CSNK2A1 (0.55) CSNK2A1SMN1; SMN2GLABACE1
SCHEMBL9291695 0.69 TP53 (0.45) CSNK2A1SMN1; SMN2LMNATP53PDK2
SCHEMBL8958913 0.68 LTA4H (0.63) CSNK2A1SMN1; SMN2GLATP53MRGPRX4
SCHEMBL8959042 0.68 CSNK2A1 (0.50) CSNK2A1SMN1; SMN2GLAHPGD
SCHEMBL18924248 0.68 MAPT (0.59) CSNK2A1SMN1; SMN2GLAATMTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed