Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603250 | 0.85 | HDAC3 (0.42) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL10625651 | 0.82 | SYK (0.43) | PPARGPPARANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1609729 | 0.80 | HDAC3 (0.46) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL10626852 | 0.79 | SYK (0.44) | NPC1RAB9ASMN1; SMN2CTSSCTSK | |
| SCHEMBL29044862 | 0.77 | PPARG (0.58) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL27349797 | 0.76 | APAF1 (0.50) | NPC1RAB9ASMN1; SMN2REN | |
| SCHEMBL10625625 | 0.75 | NPC1 (0.47) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL10883348 | 0.74 | PPARA (0.54) | PPARGPPARASMN1; SMN2RENCTSS | |
| SCHEMBL9468935 | 0.74 | CYP1A2 (0.37) | PPARGPPARARENCTSSCTSK | |
| SCHEMBL2899548 | 0.74 | PPARA (0.54) | PPARGPPARASMN1; SMN2RENCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423649-B1 | Peptides and use thereof | KURARAY CO (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5194586-A | Adult T Cell Leukemia Associated Antigen | KURARAY CO., LTD. (JP) | 1993-03-16 | — | — | US | disclosed |
| EP-0423649-A1 | Peptides and use thereof | Kuraray Co., Ltd. (JP) | 1991-04-24 | — | — | EP | disclosed |