Dymanthine

Dymanthine

SCHEMBL8959220

CCCCCCCCCCCCCCCCCCN(C)C.CCCCCCCCCCCCCCCCCCN(C)C.O=S(=O)(O)c1cccc2c(S(=O)(=O)O)cccc12

nearest known ligand 0.47

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.47
CYP2C19 P33261 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
MEN1 O00255 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
KMT2A Q03164 1/20 0.47
TTR P02766 1/20 0.46
DNM1 Q05193 5/20 0.46
THRB P10828 6/20 0.43
THRA P10827 3/20 0.43
HTR6 P50406 2/20 0.41
HTT P42858 1/20 0.39
HIF1A Q16665 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dymanthine SCHEMBL8959224 1.00 CYP1A2 (0.47) CYP1A2CYP2C19TDP1MEN1TP53
Dymanthine SCHEMBL9841230 0.81 LIPG (0.45) DNM1THRBTHRAHTR6
Dodecane SCHEMBL7645849 0.80 SCN1A (0.49) CYP1A2CYP2C19TDP1MEN1TP53
SCHEMBL5016479 0.79 TTR (0.47) CYP1A2CYP2C19TDP1MEN1TP53
SCHEMBL7949063 0.79 DNM1 (0.40) DNM1THRBTHRAHTR6RECQL
SCHEMBL29198075 0.79 CYP1A2 (0.47) CYP1A2CYP2C19TDP1MEN1TP53
Decanoic Acid SCHEMBL26131119 0.79 CYP1A2 (0.52) CYP1A2CYP2C19TDP1MEN1TP53
SCHEMBL4937511 0.79 CYP1A2 (0.47) CYP1A2CYP2C19TDP1MEN1TP53
SCHEMBL8959262 0.79 CYP1A2 (0.47) CYP1A2CYP2C19TDP1MEN1TP53
Dymanthine SCHEMBL11466359 0.78 TSHR (0.52) TDP1TSHRDNM1THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5545502-A CONTAINING SPECIFIED QUATERNARY AMMONIUM SALT AS CHARGE CONTROL AGENT MITSUBISHI CHEMICAL CORPORATION (JP) 1996-08-13 US disclosed
EP-0602566-B1 Electrostatic image-developing toner MITSUBISHI CHEM CORP (JP) 1996-07-31 EP disclosed
EP-0602566-A1 Electrostatic image-developing toner Mitsubishi Chemical Corporation (JP) 1994-06-22 EP disclosed