Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | PTPRE | P23469 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323307 | 0.83 | CYP1A2 (0.39) | MAP2K1MAP2K2 | |
| SCHEMBL7329535 | 0.79 | CA1 (0.42) | NPSR1FOLH1LMNAL3MBTL1CA1 | |
| SCHEMBL9317706 | 0.79 | GCG (0.44) | MAP2K1MAP2K2LMNA | |
| SCHEMBL9318985 | 0.79 | AKR1C3 (0.48) | LMNATDP1 | |
| SCHEMBL7326655 | 0.77 | FFAR1 (0.45) | LMNACA1CA2 | |
| SCHEMBL9317620 | 0.76 | AKR1C3 (0.47) | MAP2K1MAP2K2NR1H4PPARGPPARA | |
| SCHEMBL2384775 | 0.76 | PTPRC (0.64) | MAP2K1MAP2K2PTPRCPTPN2PTPN1 | |
| SCHEMBL7325460 | 0.75 | PTPRC (0.38) | MAP2K1MAP2K2PTPRCPTPN2PTPN1 | |
| SCHEMBL7328964 | 0.73 | MAP2K1 (0.38) | MAP2K1MAP2K2PTPRCPTPN2PTPN1 | |
| SCHEMBL6706077 | 0.72 | KDM4E (0.64) | MAP2K1MAP2K2PTPRCPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-B1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII B III A RECEPTOR | GENENTECH INC (US) | 1996-01-24 | — | — | EP | disclosed |