Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 8/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322908 | 0.87 | PTGS2 (0.43) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL9317706 | 0.85 | GCG (0.44) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL9319038 | 0.83 | CTSV (0.71) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL9317620 | 0.82 | AKR1C3 (0.47) | AKR1C3AKR1C2 | |
| SCHEMBL8959409 | 0.79 | NPSR1 (0.40) | LMNATDP1 | |
| SCHEMBL7322396 | 0.76 | ALDH1A1 (0.45) | AKR1C3AKR1C2MAPTLMNAPOLB | |
| SCHEMBL7326028 | 0.75 | MAPT (0.41) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL5676620 | 0.74 | MEN1 (0.75) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL7326942 | 0.72 | KMT2A (0.41) | MEN1KMT2ALMNAHPGDHSD17B10 | |
| SCHEMBL7332598 | 0.72 | AKR1C3 (0.43) | AKR1C3AKR1C2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII b?III a? RECEPTOR. | GENENTECH INC (US) | 1994-08-17 | — | — | EP | disclosed |