Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | GCGR | P47871 | 6/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | HSPH1 | Q92598 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332598 | 0.85 | AKR1C3 (0.43) | AKR1C3AKR1C2TRPV1PPARAPPARD | |
| SCHEMBL9317706 | 0.85 | GCG (0.44) | AKR1C3AKR1C2GCGRMAP2K2MAP2K1 | |
| SCHEMBL9318985 | 0.82 | AKR1C3 (0.48) | AKR1C3AKR1C2 | |
| SCHEMBL8959409 | 0.76 | NPSR1 (0.40) | PPARAPPARGNR1H4MAP2K2MAP2K1 | |
| SCHEMBL7322396 | 0.72 | ALDH1A1 (0.45) | AKR1C3AKR1C2 | |
| SCHEMBL5782704 | 0.71 | SIRT5 (0.53) | EPHX2GCGRPPARA | |
| SCHEMBL7330066 | 0.71 | KCNQ2 (0.47) | EPHX2PPARAPPARGPPARD | |
| SCHEMBL7329535 | 0.71 | CA1 (0.42) | — | |
| SCHEMBL7326028 | 0.70 | MAPT (0.41) | AKR1C3AKR1C2 | |
| SCHEMBL7325535 | 0.70 | MAPT (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII b?III a? RECEPTOR. | GENENTECH INC (US) | 1994-08-17 | — | — | EP | disclosed |