Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363243 | 0.90 | ITGB3 (0.55) | ITGB3ITGA2BHDAC1HDAC6HDAC8 | |
| SCHEMBL7325550 | 0.90 | ITGB3 (0.46) | ITGB3ITGA2BF2 | |
| Trifluoroacetic Acid SCHEMBL8959426 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BHDAC1HDAC6HDAC8 | |
| SCHEMBL9009507 | 0.81 | ITGB3 (0.42) | ITGB3ITGA2BHDAC1HDAC6HDAC8 | |
| SCHEMBL7322398 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7325545 | 0.79 | ITGB3 (0.55) | ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7363241 | 0.79 | ITGB3 (0.66) | ITGB3ITGA2BHDAC1HDAC6HDAC8 | |
| Trifluoroacetic Acid SCHEMBL7326019 | 0.78 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL9009406 | 0.78 | ITGB3 (0.61) | ITGB3ITGA2B | |
| SCHEMBL7356626 | 0.78 | SIRT2 (0.35) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-B1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII B III A RECEPTOR | GENENTECH INC (US) | 1996-01-24 | — | — | EP | disclosed |