Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959444 | 0.92 | KDM1A (0.34) | CYP3A4CYP2C9FPR2FASNAPP | |
| SCHEMBL13000785 | 0.92 | CYP3A4 (0.34) | CYP3A4CYP2C9FPR2FASNAPP | |
| SCHEMBL19985406 | 0.90 | DGAT1 (0.35) | CYP3A4CYP2C9FPR2 | |
| SCHEMBL13000778 | 0.90 | CYP3A4 (0.31) | CYP3A4CYP2C9 | |
| SCHEMBL8959519 | 0.90 | CYP3A4 (0.33) | CYP3A4CYP2C9FPR2FASNAPP | |
| SCHEMBL8959446 | 0.89 | FPR2 (0.33) | CYP3A4CYP2C9FPR2FASN | |
| SCHEMBL8959461 | 0.88 | PTGES (0.32) | CYP3A4CYP2C9FASN | |
| SCHEMBL8959470 | 0.88 | PDE4A (0.32) | CYP3A4CYP2C9 | |
| SCHEMBL8959466 | 0.88 | PPARD (0.31) | FPR2FASN | |
| SCHEMBL8959378 | 0.87 | CYP3A4 (0.34) | CYP3A4CYP2C9FASNAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |