Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 9/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331430 | 0.87 | PTPN1 (0.35) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL9318010 | 0.81 | KDM4E (0.50) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL8959490 | 0.81 | KDM4E (0.41) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL7357560 | 0.81 | KDM4E (0.41) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL9281590 | 0.80 | KDM4E (0.40) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL7324461 | 0.79 | TNF (0.37) | KDM4EALOX15TSHRSIRT1ALDH1A1 | |
| SCHEMBL7365574 | 0.79 | ITGB3 (0.46) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL7359240 | 0.79 | ITGB3 (0.56) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL7356371 | 0.79 | ITGB3 (0.49) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL8836989 | 0.79 | ITGB3 (0.73) | KDM4EALOX15TSHRSIRT1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-B1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII B III A RECEPTOR | GENENTECH INC (US) | 1996-01-24 | — | — | EP | disclosed |