Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318151 | 0.90 | MDM2 (0.46) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL9319073 | 0.87 | MDM2 (0.41) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL7332495 | 0.87 | ALDH1A1 (0.40) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL8959460 | 0.81 | KDM4E (0.47) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL7322450 | 0.79 | KDM4E (0.43) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL7326762 | 0.77 | AGTR1 (0.39) | KDM4ETSHRMDM2POLBMAPT | |
| SCHEMBL7329007 | 0.76 | ALDH1A1 (0.37) | KDM4EMEN1KMT2APOLBMAPT | |
| SCHEMBL7332551 | 0.74 | PPARD (0.41) | ALOX15MDM2MEN1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7333942 | 0.73 | ITGB3 (0.70) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL7329841 | 0.72 | ITGB3 (0.44) | KDM4EALOX15TSHRSIRT1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII b?III a? RECEPTOR. | GENENTECH INC (US) | 1994-08-17 | — | — | EP | disclosed |