Glycerin

Glycerin

SCHEMBL8959478

CCC(CO)(CO)CO.OCC(O)CO.OCCCCCCCO

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.39
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
HSD17B10 Q99714 1/20 0.39
TSHR P16473 1/20 0.39
THRB P10828 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.35
USP2 O75604 1/20 0.34
VDR P11473 1/20 0.32
CYP2D6 P10635 2/20 0.31
KDM4E B2RXH2 2/20 0.31
SPHK1 Q9NYA1 1/20 0.31
GMNN O75496 1/20 0.31
POLB P06746 1/20 0.31
THPO P40225 1/20 0.31
MTOR P42345 1/20 0.31
BLM P54132 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5705598 0.89 THRB (0.42) LMNAALDH1A1MEN1KMT2AHSD17B10
Glycerin SCHEMBL330202 0.89 LMNA (0.50) LMNAALDH1A1TSHRTHRBUSP2
Glycerin SCHEMBL995830 0.89 LMNA (0.50) LMNAALDH1A1TSHRTHRBUSP2
Glycerin SCHEMBL7954956 0.86 LMNA (0.47) LMNAALDH1A1TSHRTHRBUSP2
Glycerin SCHEMBL28068047 0.86 LMNA (0.47) LMNAALDH1A1TSHRTHRBUSP2
1,6-Hexanediol SCHEMBL2733820 0.86 ALDH1A1 (0.50) LMNAALDH1A1MEN1KMT2AHSD17B10
SCHEMBL28113712 0.86 ALDH1A1 (0.50) LMNAALDH1A1MEN1KMT2AHSD17B10
1,5-Pentanediol SCHEMBL484472 0.86 ALDH1A1 (0.50) LMNAALDH1A1MEN1KMT2AHSD17B10
SCHEMBL6673802 0.86 ALDH1A1 (0.50) LMNAALDH1A1MEN1KMT2AHSD17B10
1,6-Hexanediol SCHEMBL10441623 0.84 ALDH1A1 (0.48) LMNAALDH1A1MEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0692507-A1 Flexible open-cell polyurethane foam BASF CORPORATION (US) 1996-01-17 EP disclosed