Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9573821 | 0.81 | TUBB4A (0.51) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL9229422 | 0.80 | TUBB4A (0.36) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3830749 | 0.77 | MAPT (0.46) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL8959611 | 0.76 | MCL1 (0.43) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL19331084 | 0.73 | MEN1 (0.41) | MEN1KMT2AALDH1A1POLBMCL1 | |
| SCHEMBL7778483 | 0.73 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL3255506 | 0.72 | GPR17 (0.55) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL29613774 | 0.71 | MAP2 (0.42) | ALDH1A1KDM4EMAPTTUBB4ATUBB | |
| SCHEMBL6291860 | 0.70 | MEN1 (0.60) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL31171910 | 0.69 | EIF4A3 (0.43) | ALDH1A1KDM4EHPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494928-A | FOR CENTRAL NERVOUS SYSTEM DISORDERS, BLOCKING SEROTONIN RECEPTORS, ANTIDEPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | disclosed |
| EP-0655440-A2 | 1-Aminoethylindoles | F. HOFFMANN-LA ROCHE AG (CH) | 1995-05-31 | — | — | EP | disclosed |