Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959944 | 0.99 | THRA (0.45) | THRATHRBMEN1NPC1ALDH1A1 | |
| SCHEMBL8960058 | 0.97 | MEN1 (0.42) | THRATHRBMEN1NPC1ALDH1A1 | |
| SCHEMBL8959916 | 0.92 | MAOA (0.40) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL8959917 | 0.86 | MAOA (0.42) | MEN1ALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL11357497 | 0.72 | THRA (0.54) | THRATHRBMEN1NPC1ALDH1A1 | |
| SCHEMBL11354421 | 0.72 | THRA (0.54) | THRATHRBMEN1NPC1ALDH1A1 | |
| SCHEMBL8143543 | 0.72 | THRA (0.54) | THRATHRBMEN1NPC1ALDH1A1 | |
| SCHEMBL805440 | 0.72 | MAOB (0.45) | THRATHRBMEN1NPC1ALDH1A1 | |
| SCHEMBL805442 | 0.71 | MEN1 (0.56) | THRATHRBMEN1NPC1ALDH1A1 | |
| SCHEMBL4894161 | 0.70 | NPC1 (0.53) | THRATHRBMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510456-A | Bridged cyclic arleneethylene polymers | SHOWA DENKO K. K. (JP) | 1996-04-23 | — | — | US | disclosed |