Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 12/20 | 0.40 |
| ▸ | MAOA | P21397 | 11/20 | 0.40 |
| ▸ | THRA | P10827 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959792 | 0.97 | THRA (0.43) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL8959944 | 0.96 | THRA (0.45) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL8959916 | 0.94 | MAOA (0.40) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL8959917 | 0.89 | MAOA (0.42) | MEN1ALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8959924 | 0.77 | AAK1 (0.36) | ALDH1A1MAPTKMT2AMAOBMAOA | |
| SCHEMBL805440 | 0.74 | MAOB (0.45) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL805442 | 0.73 | MEN1 (0.56) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL4894161 | 0.72 | NPC1 (0.53) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL7882709 | 0.70 | MAOA (0.74) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL11357497 | 0.68 | THRA (0.54) | MEN1NPC1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510456-A | Bridged cyclic arleneethylene polymers | SHOWA DENKO K. K. (JP) | 1996-04-23 | — | — | US | disclosed |