SCHEMBL8960009

SCHEMBL8960009

C#CCN1C(=O)COc2cc(F)c(-n3c(S)nc(C(F)(F)F)cc3=O)cc21

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.34
DRD3 P35462 1/20 0.34
CHRM1 P11229 1/20 0.32
RORC P51449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9427475 0.79 BCAT1 (0.41)
SCHEMBL39263 0.78 CHRM1 (0.35) CHRM1RORC
SCHEMBL9032890 0.78 CHRM1 (0.32) CHRM1RORC
SCHEMBL9478454 0.77 SLC5A1 (0.36) DRD2DRD3
SCHEMBL7894272 0.76 CHRM1 (0.32) CHRM1
SCHEMBL10653573 0.75 CHRM1 (0.36) CHRM1
SCHEMBL4681334 0.75 CHRM1 (0.33) CHRM1
SCHEMBL15779803 0.75 CHRM1 (0.37) CHRM1
SCHEMBL4682695 0.74 CHRM1 (0.34) CHRM1RORC
SCHEMBL9597908 0.74 TP53 (0.36) CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5532208-A HERBICIDES SUMITOMO CHEMICAL CO., LTD. (JP) 1996-07-02 US disclosed
US-5366955-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-22 US disclosed
EP-0568041-A1 Pyrimidone derivatives and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-03 EP disclosed