Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11626560 | 0.96 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3158365 | 0.88 | KDM4E (0.56) | KDM4EALDH1A1HPGDLMNAHTR2A | |
| Ammonia Solution, Strong SCHEMBL28905550 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1HPGDLMNAHTR2A | |
| SCHEMBL4127686 | 0.84 | ADRA1A (0.39) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17770807 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL19932028 | 0.82 | CES1 (0.39) | MEN1KMT2AADRA1DADRA1AADRA1B | |
| SCHEMBL5901047 | 0.81 | F3 (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11627586 | 0.80 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDADRA1DADRA1A | |
| SCHEMBL21872026 | 0.80 | HTR2A (0.42) | ALDH1A1MEN1KMT2AADRA1ALMNA | |
| SCHEMBL9814145 | 0.79 | ADRA1D (0.43) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534536-B1 | Process for the preparation of 2-amino-5,6-dimethoxy-tetralin | ZAMBON SPA (IT) | 1996-01-31 | — | — | EP | disclosed |
| US-5221770-A | PROCESS FOR THE PREPARATION OF 2-AMINO-5,6-DIMETHOXY-TETRALIN | ZAMBON GROUP S.P.A. (IT) | 1993-06-22 | — | — | US | disclosed |
| EP-0534536-A2 | Process for the preparation of 2-amino-5,6-dimethoxy-tetralin | ZAMBON GROUP S.p.A. (IT) | 1993-03-31 | — | — | EP | disclosed |