Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960189 | 0.94 | KMT2A (0.41) | CYP3A4CYP2D6KMT2AMAPTMEN1 | |
| SCHEMBL8959929 | 0.88 | NQO1 (0.39) | CYP3A4KMT2AMAPTMEN1NPC1 | |
| SCHEMBL8960024 | 0.80 | CYP1A1 (0.40) | CYP3A4CYP2D6KMT2AMAPTMEN1 | |
| SCHEMBL8959946 | 0.77 | GPR3 (0.42) | CYP3A4ALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL14231474 | 0.70 | MEN1 (0.51) | CYP3A4CYP2D6KMT2AMAPTMEN1 | |
| SCHEMBL7756217 | 0.70 | CYP2D6 (0.42) | CYP3A4CYP2D6KMT2AMAPTMEN1 | |
| SCHEMBL339126 | 0.67 | MEN1 (0.65) | KMT2AMAPTMEN1NPC1ALDH1A1 | |
| SCHEMBL19809314 | 0.65 | CA12 (0.59) | CYP3A4CYP2D6CA12CA1CA2 | |
| SCHEMBL29779708 | 0.65 | CA12 (0.59) | CYP3A4CYP2D6CA12CA1CA2 | |
| SCHEMBL2151879 | 0.65 | NR5A1 (0.53) | KMT2AMAPTMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510456-A | Bridged cyclic arleneethylene polymers | SHOWA DENKO K. K. (JP) | 1996-04-23 | — | — | US | disclosed |