Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960094 | 0.94 | CYP3A4 (0.41) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL8959929 | 0.88 | NQO1 (0.39) | KMT2AMEN1CA12CA1CA6 | |
| SCHEMBL7756219 | 0.70 | KMT2A (0.43) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL338731 | 0.67 | LTA4H (0.60) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL8959916 | 0.66 | MAOA (0.40) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL22325684 | 0.65 | CA12 (0.59) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL8560597 | 0.64 | MAPT (0.49) | KMT2AMEN1CA12CA1CA2 | |
| 1,4-Dipropoxybenzene SCHEMBL122039 | 0.64 | LTA4H (0.67) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL4887538 | 0.64 | SLC2A1 (0.48) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL5248264 | 0.64 | LTA4H (0.43) | KMT2AMEN1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510456-A | Bridged cyclic arleneethylene polymers | SHOWA DENKO K. K. (JP) | 1996-04-23 | — | — | US | disclosed |